We have discussed the delivery of potent anti-scar drugs into the depths of hypertrophic scars with lasers and radiofrequency devices. The machines make hundreds of small channels through which medications may be administered directly. Drugs that have been given in this way include steroids such as triamcinalone acetate, 5-fluouracil, collagenases and platelet-rich plasma. Now, ultrasound energy has been used to push such drugs more deeply into the skin. In an article in the journal Lasers Surgery and Medicine, Trelles and colleagues showed that after holes had been created deep within the skin - in this case by using radiofrequency energy - ultrasound results in an effective and simple way of driving medications more deeply for problematic scars. ...